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in HealthResearchers discuss disrupting NKG2A:HLA-E interactions for enhanced anti-cancer immunity
Cancer therapeutics concentrating on the NKG2A:HLA-E axis. The NKG2A:HLA-E interplay may be inhibited by antibodies concentrating on both NKG2A (monalizumab, BMS-986315) or HLA-E (3H4, TFL-033). Small molecule inhibitors bortezomib and selinexor have been proven to cut back floor expression of HLA-E, sensitizing tumor cells to NK cell cytotoxicity. The proteasome inhibitor bortezomib induces endoplasmic reticulum […] More
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in PakistanPM Shehbaz meets Meta delegation to discuss IT, AI collaboration
Prime Minister Shehbaz Sharif held a gathering with a five-member delegation from Meta, led by Vice President for Asia Pacific, Simon Milner, on Tuesday. The assembly targeted on exploring alternatives for collaboration within the fields of Information Technology (IT) and Artificial Intelligence (AI) in Pakistan. During the discussions, PM Shehbaz highlighted the immense potential inside […] More